The Chemical Biology of Long Noncoding RNAs

English | ISBN: 3030447421 | 2020 | 554 pages | EPUB, PDF | 28 MB + 11 MB
This book offers a comprehensive and detailed overview of various aspects of long non-coding RNAs. It discusses their emerging significance in molecular medicine, ranging from human cancers to cardiovascular and metabolic diseases.
Transcriptomic studies have demonstrated that the majority of genomes found in complex organisms are expressed in highly dynamic and cell-specific patterns, producing huge numbers of intergenic, antisense and intronic long non-protein-coding RNAs (lncRNAs). Thousands of lncRNAs have been identified, and unlike mRNA, they have no protein-coding capacity. A large repertoire of ncRNAs, actively transcribed from the mammalian genome, control diverse cellular processes, both in terms of development and diseases, through a variety of gene regulatory mechanisms. IncRNAs have emerged as a new paradigm in epigenetic regulation of the genome.
Given its scope, the book will be of particular interest to molecular, chemical, cell and developmental biologists, as well as specialists in translational medicine involved in disease-oriented research. It also offers a valuable resource for in silico experts seeking a deeper understanding of lncRNA expression and function through computational analysis of the NGS data.
DOWNLOAD
(Buy premium account for maximum speed and resuming ability)
(Buy premium account for maximum speed and resuming ability)
Другие новости по теме:
[related-news]
[related-news]
- RNAi and Small Regulatory RNAs in Stem Cells Methods and Protocols (Methods ...
- Phosphate Labeling and Sensing in Chemical Biology
- Diversity-Oriented Synthesis Basics and Applications in Organic Synthesis, ...
- Diversity-Oriented Synthesis Basics and Applications in Organic Synthesis, ...
- Biology, Physiology and Molecular Biology of Weeds
- The Long, Long Life of Trees
- Go Long Why Long-Term Thinking Is Your Best Short-Term Strategy
- Neurobiology of Chemical Communication
- The Chemical Brothers - Come With Us (2010)
- Chemical Brothers - Further (2010)
- The Chemical Brothers 2010 - Further
- Chemical Brothers - Further (2010)
- The Chemical Brothers - Come With Us (2010)
- The Chemical Brothers - Further (2010)
- An Introduction to Chemical Kinetics